4-pyridinecarboxylic acid, 3,5-dibromo- - Names and Identifiers
Name | 3,5-Dibromopyridine-4-carboxylic acid
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Synonyms | 3,5-DibromoisonicotinicAci 3,5-Dibromoisonicotinic acid 3,5-DibroMopyridine-4-carboxylic 3,5-Dibromopyridine-4-carboxylic acid 3,5-DibroMopyridine-4-carboxylic acid 3,5-Dibromo-4-pyridinecarboxylic acid 4-pyridinecarboxylic acid, 3,5-dibromo- 4-Pyridinecarboxylic acid, 3,5-dibroMo- 3,5-dibromoisonicotinic acidC6H3Br2NO2 280.90
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CAS | 13958-91-3
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InChI | InChI=1/C6H3Br2NO2/c7-3-1-9-2-4(8)5(3)6(10)11/h1-2H,(H,10,11) |
4-pyridinecarboxylic acid, 3,5-dibromo- - Physico-chemical Properties
Molecular Formula | C6H3Br2NO2
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Molar Mass | 280.9 |
Density | 2.202 |
Melting Point | 62-64℃ |
Boling Point | 409.99°C at 760 mmHg |
Flash Point | 201.755°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | White to yellow or brown powder or crystal |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.652 |
MDL | MFCD08689615 |
4-pyridinecarboxylic acid, 3,5-dibromo- - Risk and Safety
Hazard Symbols | Xn - Harmful
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Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R43 - May cause sensitization by skin contact
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
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WGK Germany | 3 |
4-pyridinecarboxylic acid, 3,5-dibromo- - Introduction
3,5-dibromo-4-picolinic acid, chemical formula C7H4Br2NO2, is an organic compound. The following is an introduction to its nature, use, formulation and safety information:
Nature:
1. Appearance: 3,5-dibromo-4-picolinic acid is a white crystalline solid.
2. Solubility: It is soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane, but insoluble in water.
3. melting point: its melting point is about 200-203 ℃.
Use:
1. Organic synthesis: 3,5-dibromo-4-picolinic acid is commonly used as an intermediate for certain organic compounds, such as the synthesis of glyphosate (a herbicide widely used in agriculture).
2. Pharmaceutical field: It can also be used to manufacture certain drugs, such as antiepileptic drugs.
Preparation Method:
A common method for preparing 3,5-dibromo-4-picolinic acid is by bromination of 4-picolinic acid. First, 4-picolinic acid is reacted with a brominating agent under appropriate reaction conditions to form 3-bromo-4-picolinic acid. The 3-bromo-4-picolinic acid is then further reacted with a brominating agent to give the target product 3,5-dibromo-4-picolinic acid.
Safety Information:
1. 3,5-dibromo-4-picolinic acid is irritating, avoid direct contact with skin and eyes. Wear appropriate personal protective equipment such as protective gloves and goggles during operation.
2. in the process of storage and handling, to avoid contact with strong oxidants, strong acid and strong alkali, so as to avoid dangerous reaction.
3. In the event of accidental exposure to the compound, immediately flush the affected area with plenty of water and seek medical help.
Last Update:2024-04-09 21:01:54